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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MBD4
All Species:
6.36
Human Site:
T246
Identified Species:
15.56
UniProt:
O95243
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95243
NP_003916.1
580
66051
T246
K
G
I
P
I
K
K
T
K
K
G
C
R
K
S
Chimpanzee
Pan troglodytes
XP_001144095
580
66029
T246
K
G
I
P
I
K
K
T
K
K
G
C
R
K
S
Rhesus Macaque
Macaca mulatta
XP_001116090
537
61569
K210
L
K
G
I
P
I
K
K
T
K
K
R
C
R
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2D7
554
62559
R220
E
K
R
R
K
S
K
R
K
V
T
V
L
K
G
Rat
Rattus norvegicus
Q00566
492
53029
P165
T
V
T
G
R
G
S
P
S
R
R
E
Q
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506061
435
49137
D108
F
L
K
L
E
D
F
D
F
T
T
P
S
K
S
Chicken
Gallus gallus
NP_990024
416
45436
S89
A
G
G
R
A
R
R
S
S
A
R
S
D
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783908
550
62272
P217
P
T
K
S
E
T
R
P
A
K
R
S
P
S
K
Poplar Tree
Populus trichocarpa
XP_002331937
249
28474
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_974253
445
51117
S118
I
T
T
S
N
L
V
S
P
Q
I
A
D
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
86.7
N.A.
N.A.
65.6
23.4
N.A.
34.4
39.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
99.8
88.2
N.A.
N.A.
73.9
37.9
N.A.
46
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
13.3
N.A.
N.A.
20
6.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
26.6
20
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
20
N.A.
N.A.
23.1
N.A.
N.A.
Protein Similarity:
28.9
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
10
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
20
10
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
0
20
10
10
% D
% Glu:
10
0
0
0
20
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% F
% Gly:
0
30
20
10
0
10
0
0
0
0
20
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
20
10
20
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
20
20
20
0
10
20
40
10
30
40
10
0
0
50
20
% K
% Leu:
10
10
0
10
0
10
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
20
10
0
0
20
10
0
0
10
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% Q
% Arg:
0
0
10
20
10
10
20
10
0
10
30
10
20
10
0
% R
% Ser:
0
0
0
20
0
10
10
20
20
0
0
20
10
10
30
% S
% Thr:
10
20
20
0
0
10
0
20
10
10
20
0
0
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _